Temperature and Excitability

Membrane excitability: made temperature-dependent by mutations.

Three mutants of Paramecium aurelia with genetic lesions at two unlinked loci lost their ability to generate action potentials when grown at high temperatures. Action potentials found at room temperature were slightly aberrant. Kinetics of phenotypic changes after temperature shifts showed that excitation is not immediately sensitive to temperature change in these mutants. The initiation of an ...

Influence of Temperature on Neuronal Excitability in Cochlear Nucleus

The influence of temperature on neuronal excitability is studied by numerical simulations on the spiking threshold characteristics of bushy cells in cochlear nucleus periodically stimulated by synaptic currents. The results reveal that there is a cut-off frequency for the spiking of bushy cell in a specific temperature environment, corresponding to the existence of a critical temperature for th...

P3: Neuronal Death Following Posttraumatic Excitability and Seizure

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Temperature Effects on Membrane Chloride Conductance and Electrical Excitability of Lizard Skeletal Muscle Fibres

1. Intracellular recording techniques were used to study the effects of temperature on resting membrane conductances, electrical excitability and synaptic efficacy in fast-glycolytic (FG) skeletal muscle fibres from the lizard Dipsosaurus dorsalis. 2. The conductance of the resting muscle membrane to chloride ions (gci) increased from 488/iScm" at 15°C (pH7-8) to 730/iScm~ at 45°C (pH7-4), yiel...

Model membranes and excitability.